Obesity, maternal smoking and SHBG in neonates

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Obesity, maternal smoking and SHBG in neonates

BACKGROUND Sex hormone binding globulin (SHBG), a glycoprotein produced by hepatocytes that transports testosterone and other steroids in plasma, is a marker for developing metabolic syndrome and T2DM. SHBG is present in umbilical cord blood where it may be epigenetically regulated. This study was conducted to investigate whether the fetal environment, based on maternal pre-pregnancy weight, pr...

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Maternal smoking during pregnancy and childhood obesity.

A recent cohort study suggested that maternal smoking during pregnancy might be a risk factor for childhood obesity. Data from the obligatory school entry health examination in six Bavarian (Germany) public health offices in 1999-2000 were used to assess the relation between maternal smoking during pregnancy and childhood obesity (n = 6,483 German children aged 5.00-6.99 years). A body mass ind...

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Fetal environment and subsequent obesity: a study of maternal smoking.

BACKGROUND The intrauterine environment may influence the development of obesity, but as yet, the long-term effect of growth in utero is unclear. We studied maternal smoking during pregnancy to gain insight on how an insult affecting fetal growth might subsequently influence obesity risk through childhood to age 33. METHODS Data from the 1958 British birth cohort (all births in England, Wales...

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ژورنال

عنوان ژورنال: Diabetology & Metabolic Syndrome

سال: 2016

ISSN: 1758-5996

DOI: 10.1186/s13098-016-0158-0